Is It Really Dangerous to Mix Uppers and Downers?
On This Page: CNS Depression Risks of Mixing Addiction to Multiple Drugs Free Addiction Hotline Uppers and downers are slang terms that refer to how a particular substance affects the central nervous system (CNS). The Drug Enforcement Administration (DEA) refers to uppers and downers as stimulants and depressants respectively, and DEA fact sheets list the […]