Drugs are prescribed with the expectation that they will be appropriately used by the patient, for the alleviation of whatever condition necessitated the prescription.

If that remained the case, prescription drug abuse would not be one of the biggest health care problems facing the United States today. A combination of need, potency, and recklessness can make any drug a source of addiction. The line between healthy and unhealthy consumption can be disarmingly small, and with a powerful drug like tramadol, the question of when tramadol use becomes abuse is an important one that needs to be understood before using it.

Intro to Tramadol

What is tramadol? To start, it is the generic name for a prescription pain reliever that is sold as Ultram, Ultram ER, Conzip and Rybix ODT. Because it comes from a category of drugs known as opiate narcotic analgesics, it is used for the treatment of moderate to severe levels of pain. Within one hour of consumption, says the journal of Drugs, the effects of tramadol are felt. Patients are advised to take 50 mg to 100 mg every four to six hours, although more frequent consumption may be prescribed for conditions like osteoarthritis, where pain levels are more chronic.

Like any prescription medication, tramadol is powerful enough to cause a number of side effects, even when taken in moderation. As a result, patients may experience:

  • Nausea
  • Constipation
  • Dizziness
  • Drowsiness
  • Sweating

These effects should not be a cause for alarm, although a doctor or pharmacist should be informed if the effects persist or if they become excessive.

The journal concludes by saying that tramadol lacks the potential for being significantly abused (contrasted to other prescription narcotics), but there are enough concerns about risky use of the drug that, in 2010, the U.S. Food & Drug Administration and Janssen Pharmaceuticals (tramadol’s approved manufacturer) advised doctors not to prescribe tramadol to patients who are suicidal, suffering from depression, at risk for addiction, or who currently take tranquilizers or depressants.

This is because, notwithstanding tramadol’s relative safety, the opioid constituents of the drug can give users the same kind of narcotic-like high that they can get from other opioids, both legal and illegal. To that effect, a Chinese medical journal found that there is a high potential for abusing tramadol among people who are already addicted to opioids.

Unfortunately, this does create the possibility of excessive and risky use of tramadol to the point of physical danger. In 2011, says Medpage Today, 20,000 emergency hospitalizations were attributed to the improper use of tramadol (high doses of tramadol can stop breathing and can cause seizures, reports ABC News). That same year (2011), there were 379 overdose deaths in the state of Florida where tramadol was found to be a factor.

Tramadol and the DEA

mental consequences of tramadol abuseWith this in mind, and despite the initial perception of tramadol being a comparatively safe drug, the U.S. Drug Enforcement Administration classified it as a Schedule IV substance in 2014.

As part of the process to schedule tramadol, a multi-agency prescription drug abuse task force told the DEA that tramadol is a loophole drug, meaning that many patients and doctors were unaware of the dangers of tramadol because there had been little regulation surrounding its distribution and prescription (and, as with most cases of prescription drug abuse, there is a lack of understanding that such medications can be life-threatening if taken improperly). However, the task force described tramadol as a drug that could cause addiction, a drug that could be abused, and a drug that could be used for purposes beyond its medical intentions (a situation known as “diversion”).

An example of how tramadol can be misused was reported by the Egyptian Journal of Forensic Sciences. In 2010, an “increasingly alarming phenomenon” of Egyptian youths taking tramadol for various reasons related to sexual functioning (remedying premature ejaculation, prolonging orgasm and generally increasing sexual pleasure) was attributed to its wide availability and promotion, implying a widespread lack of knowledge about the proper uses of tramadol and its dangers. Al-Jazeera describes how many young men simply use tramadol as an energy boost, paying $3 for 10 pills, even as the head researcher in Egypt’s National Research Addiction Program explains that tramadol creates an extreme dependency in its users, even greater than that associated with heroin.

There is enough support for tramadol (among advocates for elderly patients, for example, or prescribers who fear that complete regulation of the drug would create a black market and unnecessarily deter health care providers who would otherwise prescribe tramadol) for the DEA to put tramadol on its Schedule IV list. Drugs on this schedule have a relatively low potential for abuse when compared to Schedule III substances, but there is enough cause for concern to merit federal regulation.


One of the key components in the DEA’s decision to schedule tramadol as a controlled substance involves the opiate chemical compounds that make it so effective. Opioids work by binding to, and activating, specific receptors on the brain. The National Institute on Drug Abuse explains that these receptors are created naturally, and they affect the parts of the brain that deal with feelings of pain and reward-based pleasure.

When an opioid attaches itself to a receptor, it dampens the information flowing to and from the brain and the rest of the body. This is why opioids are useful in the treatment of pain, because the signals transmitting the physical distress to the brain are blocked by the presence of the opioid; however, since the patient feels good and happy with the opioids in their system, this is how an addiction can start, especially since the opioids work by triggering a sense of reward in the patient. She literally feels like she has accomplished something by taking the opioid, and the natural inclination is to take more.

Eventually, consumption of the opioid goes beyond simply alleviating pain and discomfort, and graduates to becoming the only source of pleasure that the patient feels. This is one of the key criteria for how and when even beneficial drugs can be abused, and it explains the danger of how using tramadol (which, explains The Fix, is a synthetic opioid, meaning it was designed in a laboratory to have an identical chemical structure to natural opioids) can become abusing tramadol.

The DEA’s concerns are based on the fact that, when taken in sufficient quantities and for a sufficient period of time, tramadol produces effects that are dangerously similar to other controlled drugs (such as OxyContin, which Fox News called “one of the most abused drugs” in America). The Milwaukee Journal Sentinel found that tramadol use increased from 25 million prescriptions in 2008 to 40 million in 2012.

Getting Help for Tramadol Abuse

For that reason, a patient looking to get away from tramadol would do well to leave detoxification in the hands of a doctor or staff members at a treatment center. Such professionals can help curate the actual detox process (for example, by administering a low-dose benzodiazepine as suggested by the journal of Drug and Alcohol Dependence), ensuring that the resulting withdrawal symptoms can be properly managed and mitigated.

Once the patient completes detox, a course of counseling will help her learn how she can guard against the temptation to abuse further drugs. A patient who has abused tramadol knows that there is the possibility of abusing another drug or developing a full dependence on whatever medication she is prescribed for her pain. Even though her use of tramadol was arrested before it caused serious problems, she needs to know how to take the steps to properly protect herself from such a situation ever arising again. That is why psychotherapy is an inherent part of a complete drug rehabilitation program.

If you are worried that your use of tramadol is getting out of hand, give Black Bear Lodge a call today at 855-808-6212. We have admissions coordinators standing by who can tell you what you need to know about tramadol, prescription medication and the proper limits of taking your doses. Talking to one of our trained professionals can help you take control of your health, while getting you the help you need regarding how to safely and properly manage your pain.